Quick Answer: What Are The Long Term Side Effects Of Spironolactone?

What are the adverse effects of spironolactone?

Drowsiness, dizziness, lightheadedness, stomach upset, diarrhea, nausea, vomiting, or headache may occur.

To minimize lightheadedness, get up slowly when rising from a seated or lying position.

If any of these effects persist or worsen, notify your doctor or pharmacist promptly..

How long can you take spironolactone?

Spironolactone has sufficient data to suggest that long-term use appears to be safe overall. There was one long-term study with patients who received spironolactone for up to 8 years for the treatment of acne vulgaris (Shaw and White). Spironolactone can be used as monotherapy or in combination with OCs safely.

Can spironolactone make you gain weight?

There are concerns that spironolactone can cause weight gain, but there isn’t much evidence it does. For example, the package insert for the drug doesn’t list weight gain as a side effect. Along with weight gain, many people worry that spironolactone will make their skin look worse when they first start taking it.

Does spironolactone help hair growth?

Spironolactone slows down the production of androgens. These are male sex hormones, including testosterone. Reduced production of androgens can slow down the progression of hair loss caused by androgenic alopecia. It can also encourage hair to regrow.

Can spironolactone cause hair loss?

Spironolactone does not cause hair loss for those with PCOS, it can actually help to reduce hair loss as well as reducing male-pattern hair growth and acne in women with PCOS.

Is Spironolactone bad for your liver?

Hepatotoxicity. Clinically apparent liver injury from spironolactone is rare and only a few instances have been reported as isolated case reports. The liver injury typically arises after 4 to 8 weeks of therapy and the pattern of serum enzyme elevations is usually hepatocellular or mixed.

What does spironolactone do to your hormones?

Spironolactone is a moderate antiandrogen. That is, it is an antagonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT). By blocking the AR, spironolactone inhibits the effects of androgens in the body.

Can I stop spironolactone cold turkey?

If you stop taking it suddenly: If you stop taking this drug, you may start retaining water. You may also have a sudden increase in your blood pressure. This can lead to a heart attack or stroke. If you don’t take it on schedule: If you don’t take this drug on schedule, your blood pressure might not be controlled.

Can I eat bananas on spironolactone?

Avoid taking salt substitutes that contain potassium or potassium supplements while taking spironolactone. Try to avoid foods high in potassium (such as avocados, bananas, coconut water, spinach, and sweet potato) because eating these foods may lead to potentially fatal hyperkalemia (high blood potassium levels).

Should I drink more water when taking spironolactone?

In some cases, people who take spironolactone can become dehydrated. Be sure to drink adequate water while taking spironolactone. Watch for signs of dehydration, including: excessive thirst.

Can you drink alcohol while taking spironolactone?

Notes for Consumers: It is best to limit your intake of alcohol while taking this drug. Alcohol can increase the risk for low blood pressure and dizziness. If the blood pressure drops too low, you may feel dizzy or faint, in some cases falls or fainting may occur.

Who should not take spironolactone?

You should not use spironolactone if you have kidney problems, high levels of potassium in your blood, Addison’s disease, if you are unable to urinate, or if you are also taking eplerenone. Spironolactone has caused tumors in animals but it is not known whether this could occur in people.

Will acne come back after stopping spironolactone?

Your acne can come back after taking spironolactone Spironolactone is not a cure-all pill and won’t rid you of acne forever. It is prescribed to be taken daily but according to Dr Mahto, acne can return when it is discontinued.

Is Spironolactone safe for long term use?

30 The authors concluded that long-term use of spironolactone in the treatment of AV appears to be safe. Although some side effects were relatively common, they were usually not troublesome or severe enough to result in cessation of the drug.

Is Spironolactone bad for your kidneys?

Spironolactone may worsen kidney function in patients with low to no salt in their body or in those who take other blood pressure medicines (eg, ARB, ACE inhibitor). Talk to your doctor if you have concerns about this.

Is there an alternative to spironolactone?

Amiloride and triamterene may be used instead of spironolactone. They have a direct effect on the renal tubule, impairing sodium reabsorption in exchange for potassium and hydrogen.

Does spironolactone affect your mood?

Spironolactone is known to ameliorate mood and tension headache or migraine in women with premenstrual syndrome or clinical signs of hyperandrogenism.

Can spironolactone cause eye problems?

This drug can cause certain eye problems. If left untreated, this can lead to lasting eyesight loss. If eye problems happen, signs like change in eyesight or eye pain most often happen within hours to weeks of starting this drug. Call your doctor right away if you have these signs.